It seems the same as with any "hit" driven environment. Getting a top-40 song, a top blog, the next NYT bestseller, or top iPhone app takes a lot of work and a little luck. There are those who are suited to it, persevere and get that big break. Then there are a few who just don't get lucky and thousands of wannabes who fail to execute, be it on minor flaws or epic levels.
I think the best description of the process comes from an editor explaining why so many manuscripts fail: http://nielsenhayden.com/makinglight/archives/004641.html#00...
It's harsh, but has given me insight into how the startup world, including iPhone app startups, works.