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JacobDotVI

396 karma · joined February 10, 2017

Successful entrepreneur tackling the data at the intersection of healthcare and life sciences. President of Flyrbidge.vi & VP Product @ USRetina

Previously: DARPA Grand Challenge, US Naval Research Lab, co-founder Kinsail Corp (acquired '14), and Cancer Treatment Centers of America and Co-founder Superconductive Health. hello at jacob dot vi

http://jacob.vi

http://flybridge.vi

submissionscomments
JacobDotVI··on U.S. seeks to revive idled shipyards with help of Japan, South Korea
Are there any startups working on disrupting US Shipbuilding?
JacobDotVI··on Homemade Pasta. Now Is the Time (2021)
Activity-hours aren't fungible and have constraints. If I need to eat by 6pm and get home from work at 5:30 pm, I generally can't just choose to swap a 9 - 10 pm hour of streaming with an hour of preparing food.

While some people can level up and perform food-prep activities during the 9-10 pm hour so that the following 5:30 - 6 pm slot can be filled with quick prep, many people don't know how to do so, nor see the ROI for such activity.

JacobDotVI··on My Left Kidney
Some screenings have gone direct to consumer in the US. Fairly easy to purchase online, make an appointment, then show up for a quick collection.

https://www.ondemand.labcorp.com/

https://www.questhealth.com/sale

Quest is even running a sale right now on some tests!

JacobDotVI··on The Restaurant Nearest Google
What is old is new again. The Chicago Tribune writing in 1992 about restaurants naming themselves to get a better listing in the phonebook:

"`A ALPHABETICAL ADVANTAGE` HELPS BUSINESSES" https://www.chicagotribune.com/news/ct-xpm-1992-11-08-920411...

JacobDotVI··on Meta sued by states over harmful youth marketing
Now do it for the food and candy companies
JacobDotVI··on Title 38, §1614: Products containing PFAS
Some additional information:

https://www.pressherald.com/2023/10/16/maines-pfas-law-draws...

JacobDotVI··on Ask HN: Any interesting books you have read lately?
Guzey updated changed his mind on this topic: https://guzey.com/2022-lessons/#get-minimum-possible-sustain...

It's unfortunate that he hasn't added a disclaimer to the original post since it is shared so widely.

EDIT: fixing autocorrect

JacobDotVI··on Ask HN: How to deal with 0.1X programmer colleagues?
A formula 1 race car is _much_ faster than a freight truck. However a freight truck can deliver a lot more goods across the country than an F1 car. Which is your big organization optimizing for?
JacobDotVI··on I’m a doctor: Here’s what I found when I asked ChatGPT to diagnose my patients
My hunch is that this is exactly what he was expecting. There is a lot of hype around ChatGPT passing the medical exam and this exercise is a counter point to that.
JacobDotVI··on FDIC auction for SVB said to be underway, final bids due Sunday
Not an FDIC auction, but if you’re interested in what this sort of bidding looks like the book Barbarians at the Gate details the LBO auction of RJR Nabisco. That auction was a lot of bankers squired away in conference rooms on separate floors of an office building while the auctioneers walked bids between the various groups.
JacobDotVI··on Netflix's New Chapter
He wrote a book called Blitzscaling regarding how to execute: https://www.amazon.com/Blitzscaling-Lightning-Fast-Building-...

The book Netflixed (mentioned in the article) is likely also a good source: https://www.amazon.com/Netflixed-Epic-Battle-Americas-Eyebal...

JacobDotVI··on The art of knowing when to quit
First Round had a good podcast episode with her about the book:

https://overcast.fm/+k1HEhCB1U

JacobDotVI··on WeWork exits 40 U.S. locations after tepid forecast
Try a roost stand (or equivalent) and external keyboard and track pad (I use the smallish apple ones). This has saved my posture when working from outside my office. It’s not the equivalent of the home base setup but it’s good enough that my neck isn’t screaming at me at the end of the day
JacobDotVI··on Show HN: Add live runnable code to your dev docs
This seems like a great alternative to passing around postman collections separate from documentation
JacobDotVI··on How do you fix a stroad?
> Has anyone ever put a picture of a stroad up as art/instagram etc like you see with downtown NYC, Paris, small european villages, shanghai, rural mountain towns, old downtowns in America etc?

Yes, but in a different way than I believe your question implies. Edward Burtynsky produced an amazing series of photographs centered around the automobile and in his words, how it "represent[ed] not only freedom, but also something much more conflicted."

https://www.edwardburtynsky.com/projects/photographs/oil

One of the most internet famous images from that series is of a stroad in Breezewood, PA:

https://www.edwardburtynsky.com/news-hub/2019/7/25/what-inte...

JacobDotVI··on Mushroom leather and how it is made (2020)
Some shoe brands still do this, such as Allen Edmonds:

https://www.allenedmonds.com/discover/our-story/recrafting.h...

JacobDotVI··on Ask HN: What's the quickest way to get something online?
Using s3 to host a static page?

https://docs.aws.amazon.com/AmazonS3/latest/userguide/Hostin...

JacobDotVI··on Helion
My understanding is that fusion power theoretically has net positive output, but practically no one has achieved this yet. If they are able to achieve such it would be a scientific and commercial breakthrough.
JacobDotVI··on I was terrified of an eyeball injection
Many patients need these injections regularly (every 4-6 weeks on some treatment protocols). My understanding is that it’s not safe to give some general anesthesia that often for as long as patients need these treatments (years).
JacobDotVI··on $1.5B lithium deposit discovered in Maine; excavating it poses a legal challenge
I think this is part of that distinction. Likely a gravel pit would _not_ be considered "mineral mining" and so would be permitted at a size greater than 3 acres.
JacobDotVI··on $1.5B lithium deposit discovered in Maine; excavating it poses a legal challenge
I find this more relevant:

"But [the lithium] reserves also would not present the same type of potential environmental issues as ... other base metal sulfide deposits in Maine, such as Bald Mountain. That’s because the Plumbago North deposit does not occur in, or contain, sulfide-rich rocks, said Slack and Simmons. Mining for lithium there would instead be similar to quarrying for granite or gravel."

Are rock queries outlawed? I don't believe so. Thus, is this a lithium rock query or a lithium mineral mine?

JacobDotVI··on I’ve been reading a whole lot about tomatoes
I keep hoping that one of these shipping container farms will support tomatoes due to this issue. Unfortunately, I have yet to find any (although some claim version N will be tomatoes). My hunch is that they can't grow tomatoes dense enough to make the economics work.
JacobDotVI··on I’ve been reading a whole lot about tomatoes
I wonder if they can charge more for the non-cold-chain tomatoes due to better flavor:

>Cold storage is widely used to extend shelf-life of agriculture products. For tomato, this handling results in reduced flavor quality. Our work provides major insights into the effects of chilling on consumer liking, the flavor metabolome and transcriptome, as well as DNA methylation status.

from: https://www.pnas.org/content/113/44/12580

JacobDotVI··on Visa Buys CryptoPunk #7610
>Deutsche Bank Will Sell Off 200 Modern Works From Its Corporate Collection to Pivot Its Focus to Contemporary Art

>The bank, which says it wants to buy more "up-and-coming talents," bought several works at Frieze London.

https://news.artnet.com/market/sale-deutsche-bank-1914074

JacobDotVI··on Marc Andreessen on Investing and Tech
Research in general is the same, but shouldn’t _published_ research have already gone through a filter such that it represents the 10% that hasn’t failed?
JacobDotVI··on Launch HN: BlackOakTV (YC S21) – Netflix for black people
>Hello Sunshine was founded by Witherspoon in 2016 to create content focused on female voices. ... "Kevin and Tom and our partners at Blackstone see what we see – women’s stories matter, and we have economic power as consumers, creators and business leaders. Their commitment enables us to double-down on our mission and our ambitious growth agenda,” Harden said in a release.

Reese Witherspoon’s Hello Sunshine to be sold to Blackstone-backed media company for $900 million: https://www.cnbc.com/2021/08/02/reese-witherspoons-hello-sun...

JacobDotVI··on Where are the robotic bricklayers?
Would you not consider a power drill a "partial robotic system"? Is this a situation where once something is useful it switches from being a "robot" to just a "power tool" and so "robots" are a kind of endless frontier?
JacobDotVI··on 1 out of every 153 American workers is an Amazon employee
Now do it for:

* US DoD * Walmart * McDonalds * USPS

JacobDotVI··on Visualizing all the vacant office space in San Francisco
it looks like that's included in the 17M based on the linked article:

>With all COIVD-era restrictions on office building occupancy rates having been eliminated last month, the effective office vacancy rate in San Francisco has ticked up to 20.1 percent, representing over 17 million square feet of vacant office space, with 7.76 million square feet of space which is technically leased but sitting vacant and actively being offered for sublet, which is down slightly from 7.99 million square feet of sublettable space in the first quarter of the year, and 9.33 million square feet of un-leased space, which is up from 7.97 million square feet in the first quarter, according to Cushman & Wakefield.

https://socketsite.com/archives/2021/07/over-17-million-squa...

JacobDotVI··on Why we're blind to the color blue
>This is one of many examples of our brains being much more powerful than our eyes. Too often we think of our eyes as perfect cameras. However, it is the brain that is able to accomodate [sic] for all of the optical shortcomings in order to resolve the world.

While this is a description of the human brain and human eye it's interesting to me that it is a very accurate description of the progression of camera technology in the last few years as we shift from the supremacy of Big Glass to the amazing results from computational photography being applied to cell-phone sized lenses

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