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brobdingnag_pp

10 karma · joined June 24, 2024

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brobdingnag_pp··on A chemist explains the chemistry behind decaf coffee
Coffee is laden with beta-carbolines, some of which are known to be anxiogenic.
brobdingnag_pp··on MPPP – The first 'designer drug' disaster (2023)
”Pills” is a misnomer here, we’re talking miniscule doses of powders/liquids. Sounds like they took too much MDPV.
brobdingnag_pp··on Xwax Is an Open-Source Digital Vinyl System (DVS) for Linux
Serato DJ Pro and Traktor probably
brobdingnag_pp··on Eight Years of GraphQL
That is a non-answer. Do you like pushing over gravestones too?
brobdingnag_pp··on Eight Years of GraphQL
”I've literally written RESTful Graph based data access APIs that don't do this. Multiple. At tech startups.”

Okay mr startup man, fact is you don’t know what you’re talking about and your head is so far up your startup ass you no longer know what’s good engineering.

Why are you writing your own restful graph based data access APIs?

brobdingnag_pp··on Eight Years of GraphQL
Why do you mention GraphQL and JSON:API in the same sentence? The latter is at least 10x more difficult to understand with all its edge cases around entity relations and filtering.
brobdingnag_pp··on Docs as code (2017)
Or just require file/function level comments. Requiring them to be helpful can be managed interpersonally, like someone was slacking off (they are)
brobdingnag_pp··on Supreme Court blocks controversial Purdue Pharma opioid settlement
https://link.springer.com/article/10.1007/BF02247412
brobdingnag_pp··on GitHub UX has operational security risks
Accidentally @tagging people in private PRs is always fun too!
brobdingnag_pp··on Pharma firms stash profits in Europe's tax havens
So now the politicians families own drug corporations and get preferential treatment. We have reached USA levels of corruption.
brobdingnag_pp··on Pharma firms stash profits in Europe's tax havens
And now it would be a political issue which drugs get manufactured for cheap and for whom. You can probably see how that would go in corrupted countries (i.e. all of them)
brobdingnag_pp··on Supreme Court blocks controversial Purdue Pharma opioid settlement
That is not true. It is the interaction of nicotine with various monoamine oxidase inhibitors that makes tobacco smoking addictive, to an extent that it could be stated that it is the MAOIs entirely causing the addictive behaviour: the exact same MAOIs are also found in coffee, after all.

Why are nicotine pouches and vapes addictive, then? The answer lies in the flavourings, which themselves have psychoactive properties, likely also through MAO inhibition.

brobdingnag_pp··on Supreme Court blocks controversial Purdue Pharma opioid settlement
Heroin was introduced as a cure to morphine addiction.
brobdingnag_pp··on Supreme Court blocks controversial Purdue Pharma opioid settlement
What’s weird is that people still think tobacco smoking is about nicotine being addictive and dangerous, when it is literally everything else in the smoke that makes it extremely addictive and mortally dangerous.
brobdingnag_pp··on Flow Charts with CSS Anchor Positioning
It’s essential complexity, so it’s not going anywhere.
brobdingnag_pp··on Flow Charts with CSS Anchor Positioning
That’s because print is an additive medium and requires support for additive colorspaces (CMYK) and device color profiles.
brobdingnag_pp··on New JavaScript Set Methods
Beware of a gotcha here: object keys are tested for strict equality and not deep equality, in other words add/get must use the same object instance and not just an object with the same keys/values
brobdingnag_pp··on Komorebi: Tiling Window Management for Windows
So, ”god rays”?