60 karma · joined March 24, 2008
My hypothesis is that there is too much variance in day to day life, activity, stress, food and liquid intake. In order to really test something I'd like to limit variables by using health apps for BP and HR, limiting diet by using something like Soylent for a month. That would establish the baseline test, then implement the change/drug/supplement, and test daily or weekly.
FWIW Yohimbe made me feel like shit. I would caution anyone looking at quick fixes without reading and setting up groundwork to accurately test yourself, even if its only anecdotal.
Why do I say we need to personally track things? There's a lot to learn. Is your system starved for, or already flooded with the element you're about to consume? Is your system lacking a precursor? Is your system failing downstream to break something else down which is causing a cascading build up? Everybody up-regulates and down-regulates stimulants, catacholamines, etc at different rates. Are you able to break it down from it's required co-factors upstream or downstream? As for Yohimbe, our adrenergic receptors are part of the puzzle there.
Many people have metabolic enzymatic variances, deficiencies, to full blown impairment and we all have changing levels of receptors. Some elements cross the blood brain barrier, some don't. Some people can benefit from a supplement, or an enzyme but to others it's actually detrimental since it may block another pathway. Even commonly known Dopamine and Serotonin require various ingredients that may or may not be present in our systems such as dopamine beta hydroxylase, LDopa, BH4, etc. Various receptor density in any area can impact both the uptake and down regulation, while cascading their impact neighboring systems.
We as humans, are all very different on what works, and what doesn't. It sucks, and it's amazing.
His blog also running D7 with 2 posts on Drupal, nothing on scale that I noticed quickly. http://johnhaller.com/development
30 seconds of research provides a pretty obvious connection, regardless of your "no fucking clue what they're doing" accusation...
Nilotinib is a Tyrosine Kinase Inhibitor https://en.wikipedia.org/wiki/Nilotinib
Tyrosine kinase inhibitors regulate serotonin uptake in platelets http://www.ncbi.nlm.nih.gov/pubmed/7589171
Tyrosine kinase in serotonin induced cerebral constriction http://www.ncbi.nlm.nih.gov/pubmed/9472895
It's apparent that Nilotinib plays a role with Serotonin, which is of course implicated in Parkisons and many other neurological disorders, but I guess we are hung up on cute headlines and not the real story. http://phys.org/news/2010-06-serotonin-decades-old-mystery-p...
[edit:sp]
http://searchengineland.com/google-may-discontinue-ajax-craw... March 5th: Gary said you may see a blog post at the Google Webmaster Blog as soon as next week announcing the decommissioning of these guidelines.
Pure speculation but interesting... The timing may have something to do with Wix, a Google Domains partner, who is having difficulty with their customer sites being indexed. The support thread shows a lot of talk around "we are following Google's Ajax guidelines so this must be a problem with Google". John Mueller is active in that thread so it's not out of the realm of possibility someone was asked to make a stronger public statement. http://searchengineland.com/google-working-on-fixing-problem...
Another is their SEO Report Card from a different angle: http://googlewebmastercentral.blogspot.com/2010/03/googles-s...
Moz (SEOmoz) provides another good source of info here: http://moz.com/beginners-guide-to-seo
The signup/interview through checkout process took about 30 seconds. Curiously awaiting the results. Thanks again Dan.
I would like to see them show all the reviews and separate the ones that are not approved/flushed out. Have the reviews/rankings grayed out and require the user to hit certain publicly known goals to get their reviews to be approved status. I think this approach would also help with spam as those companies that are placing and encouraging shill reviews are easily spotted.
Google recently published an internal SEO audit. The report is more or less a blueprint of what you should follow on an on-site level with your own site and I would have to imagine that was the intent.
I generally try to spend the full value of the card at once otherwise I end up with cards with random amounts, lose track, and eventually forget about them.
I see Twitter as the place news breaks, not the AP. With everyone having access to Twitter the playing field is even on breaking news stories. Maybe we should all just follow Twitter and write as many clever headlines as possible, then send the bill to the AP when they will undoubtedly use the same headline.
I have used instantdomainsearch.com in the past with some success for tld's, roughly similar idea but has been around for a long time.
Good Luck!
One thing I would point out is that everything else being equal a good domain name will generally get more clicks. The higher CTR will eventually lead to higher results in both the natural and paid results. A good domain name is also important for branding and other forms of advertising.
I am not going to remember an IP address unless my dork quota hasn't been met that week.
How about going the invitation only route? Or creating a series of basic coding/php type questions in order to sign up (think captcha)? I think either of those if implemented would cut down on the drive by comments that bring down discussion.