gnok

The implications of this video are stunning. This is the closest we have ever been to understanding the invasion process of the parasite at a molecular level. Perhaps this will finally lead to a viable and effective vaccine for Malaria. This disease is a major killer in tropical and sub-tropical regions and any real vaccine can save literally millions of lives.

The abstract is at http://www.cell.com/cell-host-microbe/abstract/S1931-3128(10... The actual PDF is at http://download.cell.com/cell-host-microbe/pdf/PIIS193131281...

EDITed for PDF link

On a Mac, you do "Alt+e e" to get the acute accent for "Résumé". To get a grave accent, use "Alt+~ e". "Alt+i e" gives you the circumflex on the e: "ê". Hope that helps anyone looking.

Some options to step out of the technology/science/engineering courses:

* A business course or two could be extremely useful depending on the course content -- you probably want to talk to a course counselor in the Business school about this.

* Take at least one art/design course. As a developer, I cannot tell you the number of times I've wished I understood design a little better. If nothing, understanding basic design principles will allow you to creatively contribute to a designer at some later date.

* Learn at least one new language. You haven't mentioned which country you're from (your profile doesn't say much), but Spanish is a good choice in the US. Personally, I wish I learnt German (I'm Indian and I find German a lot similar to Hindi and other Sanskrit-derived languages).

* Take a course that furthers your hobby: Photography, Art, Snowboarding, Archery and what have you.

* Take a course in the biology department. Preferably one that tells you more about the human body -- yourself. At the very least, you should be able to read your doctor's professional diagnoses or reports and understand what they mean. Know proximal vs distal, dorsal vs ventral and so on.

I'm sure there's more. I haven't had enough coffee to think right now though.

Unfortunately innovation as measured by patents, is measured more easily on the scale of quantity than quality. Today, patents are more like trapdoors -- the more of them you have, the higher the chance that your 'enemy' would fall into one. And this is where you let your sharks loose.

If I could ask a favor of folks compiling such documents: Please post these to a Wiki. Wiki-like interfaces are far more readable than 'shared' documents. Wikis are also inherently designed for collaboration with complete history (thus automatically working around vandalism).

Edited to complete a sentence.

Works fine for me on Chrome latest dev channel and Safari 5.0.2 on Mac. That said, I've had issues with Firefox 3.6.x with HTML5 in the past, ranging from outright incompatibility to extremely slow performance. Firefox 4.x supposedly fixes all those issues. YMMV.

Is it just me, or is the entire 'War on X' meme beginning to get annoying?

The abstract of the paper the article quotes is here: http://tinyurl.com/6bgtwu4 [sciencedirect.com link; too long to put here]

There's no real mention of any university names. This line caught my eye: "However, attendance at a super-elite university was insufficient for success in resume screens. Importing the logic of elite university admissions, firms performed a secondary resume screen on the status and intensity of candidates’ extracurricular accomplishments and leisure pursuits."

So it sounds like these 'recruiters' don't just look at what school you come from, but also look at what else you've done outside school during your years. Sounds about fair to me. HuffingtonPost article sounds like it was written in a rather sensational manner.

Google's Website Optimizer is simple and free and works nicely. Perhaps that works for you?

Sorry, I should have been more clear. I was wondering if he remembered that the script would launch PhotoBooth before he opened the lid each time. I expect he'd have just grabbed his MacBook and opened the lid and then remembered that it would take a picture.

Pretty neat hack! Were you conscious of the script each time you opened the lid? I imagine I would forget about it after the first week.

Do you have any examples of violations of Fitts law in OS X that weren't present in OS9?

That's pretty interesting. I wonder why this approach was never re-done with iPhone and MobileMe (Contact sync and Calendaring have big applications here). Perhaps there are important unsolved problems I'm overlooking.

I'd much prefer a unified view instead of sync. No connection? No problem, show me what I have in my local copy. Admittedly, there's no redundancy with unified views.

Or a wiki, more appropriately.

The second "key" is a developer's proficiency with design. I am a developer and I know little to nothing about design. This is a major distraction since I spend a disproportionate amount of time getting a barely passable design. Would anyone recommend a good design resource for developers? Books/links/blogs all work. I try to read stuff like Smashing Magazine and Core77 but I mostly feel out of depth there.

"Adam looks more male and industrial than other softer tablets out there"

Is that really a "key hardware feature"? Why would you use such an overtly sexist and insulting statement to define your product?

It isn't always 'plain and simple' to move to a different ISP. Except for very few parts of the country, most users do not have a choice of ISPs.

In your experience, how often have you seen this happen?

An app can grab the unique UUID for each device. I believe their restriction is 7 unique devices.

Original FCC release at: http://www.fcc.gov/Daily_Releases/Daily_Business/2010/db1221...

Thanks much! For me (a hobbyist looking to be an entrepreneur), your response was spot on.

Hmm. That's interesting. I can think of many products that failed essentially because no one heard of them and not because they were too expensive. I guess I didn't think too much before applying this analogy to startups.

Could you cite some interesting examples of startup failures worth reading about?

Agreed. They didn't seem to have issues finding investments or visibility. If this is one of those "other issues" cases, there's lots to learn from here.

I suspect one really good choice would have been Steve Jobs. 2010 was the year that tablets really took off. 2010 was also the year Apple's market capital exceeded Microsoft's. Perhaps next year, if Apple crosses Exxon Mobil's market cap?

(I realize market cap isn't a great metric in itself, but bringing Apple out of the 90s slump to where it is today, is a feat in itself. Becoming part of our culture and daily life, is quite another.)

To me, the phrases 'H1B' and 'startup' are inherently disconnected. I -- and many others, i imagine -- would love to read your post on your immigration issues. Thanks!

On a somewhat un-related note, I am interested in hearing about your immigration issues. I realize an immigration attorney's advice is probably golden, but I would like to hear what visa categories you considered and applied for and what problems you encountered while applying/gathering paperwork.

The footnote mentions this is a parody. And quote "Donations made will actually go to the Git project under the Software Freedom Conservancy.".

" How many people out there really make their money checking in open source code?" As an example -- Last I checked, most kernel commits were done by folks paid to write code. Similarly, most Ubuntu work is done by Cannonical; Debian, GNOME, Mono, Apache and Webkit (among many many others) all have paid open source developers.

"he needs to run .NET non-stop and copy/paste code from Reflector to his Mono implementation" That's a pretty bold claim to make. If you're not trolling, do you have solid evidence to back this up?

Out of curiosity, why do you think this is not possible?