Hacker News Reader

signal_spaceon Ask HN: How do you choose a hostname for personal devices?

amino acids, alkanes, or elements

signal_spaceon The New Internet

Any one play with https://github.com/slackhq/nebula

signal_spaceon Goldman Sachs: AI Is overhyped, expensive, and unreliable

Cult of the exponential, considers sigmoids heresy.

signal_spaceon (Pi5) M.2 HAT+ on sale now at $12

I have a pi with some amazon m.2 shield and ethernet works.

signal_spaceon We could have a superintelligence in months. 1% catastrophic risk is too large

idk squealing about exponentials seems like a thing someone whose never seen a sigmoid does…

signal_spaceon Cubic millimetre of brain mapped at nanoscale resolution

wrt to the egg - could be excreting chemicals modulating the intracellular medium

signal_spaceon Adam Curtis on the dangers of self-expression (2017)

I feel like the obvious answer here is cave paintings.

signal_spaceon AlphaFold 3 predicts the structure and interactions of life's molecules

Is alphafold doing model generation or is it just reducing a massive state space?

The current computational and systems biochemistry approaches struggle to model large biomolecules and their interactions due to the large degrees of freedom of the models.

I think it is reasonable to rely on statistical methods to lead researchers down paths that have a high likelihood of being correct versus brute forcing the chemical kinetics.

After all chemistry is inherently stochastic…

signal_spaceon Ask HN: How do I stop political SMS spam?

I always use the option to report them as spam that pops up in iMessage.

signal_spaceon I should have loved biology (2020)

check out uri alon’s introduction to systems biology

signal_spaceon Waffle House's Magic Marker System

the counter?

signal_spaceon Sonar: A Native Mac App for GitHub/Gitlab Issues

is there support for the kanban project boards planned?

signal_spaceon Microsoft completes $69B deal to buy Activision Blizzard

I wish they would finish starcraft ghost

signal_spaceon macOS Sonoma is available today

ill double check but i mentioned it on the forums and they suggested i use orion

https://kagifeedback.org/d/1708-inconsistently-redirects-to-...

signal_spaceon macOS Sonoma is available today

the only thing this update borked for me is the safari kagi plugin

signal_spaceon [dead]

man im sure this will be used for good.

signal_spaceon Microsoft Owns the Trademark for “X”

https://tsdr.uspto.gov/#caseNumber=87980831&caseType=SERIAL_...

ms sold this one to meta

signal_spaceon Nearly half of the tap water in the US is contaminated with ‘forever chemicals,’

I wonder what % of milk or dairy in general is contaminated…

signal_spaceon After Alaska Airlines planes bump runway, a scramble to ‘pull the plug’

calculation of total weight ends up being a pde right?

signal_spaceon Ask HN: Math books you recommend just for the way they are written?

Nonlinear dynamics and chaos also but Strogatz i highly recommend.

signal_spaceon Biochemical Pathways Map

not a directed acyclic graph

signal_spaceon Egg whites can be transformed into a material capable of filtering microplastics

ovalbumin purification was a undergrad biochem lab

https://en.m.wikipedia.org/wiki/Ovalbumin

suggested but unconfirmed to have a storage as a function, so it makes sense to try its hand moving waste up its gradient

signal_spaceon Novel coronavirus complete genome from the Wuhan outbreak available in GenBank

https://en.m.wikipedia.org/wiki/Polyadenylation

signal_spaceon China gene-edited baby experiment 'may have created unintended mutations'

the thing with ethical germline edits is that it implies recording all future progress of the edit.

ie continued gene level surveillance for all progeny

signal_spaceon Math Reveals the Secrets of Cells’ Feedback Circuitry

Highly recommend this text and Uri Alon's work in general for those interested in diving deeper into this subject.

https://www.amazon.com/gp/product/1439837171/ref=dbs_a_def_r...

signal_spaceon Every Cancer Patient Is One in a Billion

Many cancers are heterogeneous. Once a malignant community forms the established organized population deteriorates into chaotic competition.

signal_spaceon Landfill is underrated and recycling overrated

The issues with mason jars and ceramic cup ends up being the amount of energy required to fire the oven. This ends up putting you in a deep hole when it comes to accounting energy inputs, as consumer plastics are essentially repurposed refinery waste.

This leaves you with the choice to either spend a lot of energy or risk environmental contamination. Chemical accounting ends up being a nontrivial problem to address.

signal_spaceon Ask HN: What are your favorite YouTube channels to learn stuff?

I really enjoy math videos on youtube. https://www.youtube.com/user/MIT anything with Gil Strang is fantastic. https://www.youtube.com/channel/UCtAIs1VCQrymlAnw3mGonhw appeals to my sense of humor.

signal_spaceon DNA Data Storage Is Closer Than You Think

The signal:noise:cost function is prohibitively high.

signal_spaceon Mitchell Feigenbaum, physicist who pioneered chaos theory, has died

I highly recommend Nonlinear Dynamics and Chaos by Steven Strogatz.