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subrat_rout

195 karma · joined May 22, 2012

HTML5, CSS3, JavaScript, NodeJS, MySQL, PostgreSQL, MongoDB and Ruby on Rails. Previous experience in Healthcare, Microbiology and Drug discovery, Regulatory affairs and now doing software programming especially full stack web development. subratrout.com subrat2040<at>gmail<dot>com
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subrat_rout··on My mindfulness practice led me to meltdown (2021)
Mind disclosing the name of retreat and place where one can attend?
subrat_rout··on Hard truths I learned when I got laid off from my SWE job
If Sweden pays $115/day then it comes about $575/week. And if US pays $145/week how it is 30% more than Sweden?
subrat_rout··on GoDaddy buying domains when they expire to extort their own users
One more suggestion. Never ever search any domain you want to buy on GoDaddy. If you search something and the domain name is available and you did not buy it, then good luck getting that domain at a normal price in the future. GoDaddy generally buys it and then parks it with asking price of x100 to x1000 range.
subrat_rout··on NMN: A Stable, Reliable NAD+Activator and Anti-Aging Molecule (2020)
How are you taking it? And what does it cost?
subrat_rout··on Deploy to DigitalOcean from Glitch
That was also my initial thought. I thought it would be similar to Heroku or Hatchbox. But I see there are lots of information missing on how to deploy a Rails or Django app with databases and redis etc.
subrat_rout··on Ask HN: What would you do with $100k USD?
It all depends on your level of risk tolerance. Would you want to play safe where you do not want to loose money at all? Invest in inflation protected Treasury bonds. Currently I-bond is paying 7% return.

Would you want to play risky where you do not mind loosing a chunk of the size? Invest in a few obscured cryptos after doing some due diligence where there is a chance of 10-100x return.

Want to play safe where moderate risk is tolerable? Invest in real-estate but it also depends on market and country. People think buying a franchise will make them an entrepreneur but remember franchise is nothing but a job disguised under thin veil of entrepreneurship. In Franchise business, someone else has a major control over your business and you have to play by their playbook rule. In addition, there is a very little room to scale.

However, if you are person with some developer or marketeer skill then this is the best route to go. If you have few ideas then you can test those by developing a prototype and putting in hand of customers and getting feedback. But be aware that for each prototype you should not spend more than 5-10k. If you have sufficient time in your hand then other non conventional investments can be buying farm lands and trying organic farming, providing micro-loans to entrepreneurs etc.

subrat_rout··on Ginkgo Bioworks (YC S14) is going public today
How do you buy shares in the SPAC? Is there a minimum amount? Which platform can I use to buy shares in the SPAC?
subrat_rout··on SAP Ariba too expensive Anybody interested in building an alternative with me?
Not trying to play negative. It is not about building. Developing the product is only 10% of the game. The rest 90% lies in marketing and sales. There are several interesting HN discussions on how these complicated enterprise behemoth survive and flourish.

Moreover if you really want to attract people into your ideas you need to tell a bit more about yourself. Why should I join force with you? What are you bringing on the table?

I will add these two links below for a reference.

https://news.ycombinator.com/item?id=22244750 https://retool.com/blog/erp-for-engineers/

subrat_rout··on Ask HN: What tech stack would you recommend for a single-page web application?
I'd suggest go for the tech stack with which you are the most familiar with.
subrat_rout··on Twitter Giveaway Scammer Targeting Chamath via Hacked Verified Accounts
Agree. Big name and celebrities should held social media accountable and companies or organizations defrauding people should not get away with these kind of shenanigans.
subrat_rout··on Twitter Giveaway Scammer Targeting Chamath via Hacked Verified Accounts
Is Chamath aware of this? Why he is not putting a public statement or warning on this? Is he really giving away all those bitcoins?
subrat_rout··on Making Vaccine
Ok great to know. But my intention here is to convey that it is dangerous to biohacking a molecule/compound that a user is going to put in his/her body. The peptides after synthesis needs to be rigorously tested(QC/QA) for the desired sequences and to make sure the absence of any undesired epiotopes mixed.
subrat_rout··on Making Vaccine
I completely agree with fabian2k. It's incredibly risky to throw all random sequences peptides into the blood stream for evoking immune response. What happens if a sub-sequence of peptide matches with one of our own's body proteins and our immune system starts building antibody against it? That's what happens in most of autoimmune disease.

In addition, most of the peptides that can be synthesized from a protein structures are sequential epitopes. To ELI5, imagine a string with beads that starts with A-Z letters and we take a smaller sequence A-B-C-D or B-C-D-E and throw to system to build antibody against it. Yes, the immune system can make antibodies against it. But in real life, most of the protective or virus neutralizing antibodies comes from conformational epitopes. Imagine when the protein gets folded to its natural form then the beads with letter sequences are just jumbled sequences and finding a conformational epitope is key to raise neutralizing antibodies. That is only possible when a protein's structure is fully understood using x-ray crystallography. The article does not disclose how the author was able to get those sequences and how he was sure about its efficacy.

However, the author's bold step towards the experiment is praiseworthy. But extreme caution is needs to be taken as self administering an untested drug or vaccine may fall within the boundary of law and it can invoke regulatory actions against him.

subrat_rout··on Ask HN: How much money do you have?
Is it from stocks, IPOs or any exit? Curious!
subrat_rout··on Launch HN: Scrimba (YC S20) – Interactive video for learning to code
Great and awesome resource. Just signed up as a paid member. My only minor gripe is that most of the courses are geared towards frontend development. It would be great if founders can invite authors to develop some courses on backend development, databases and some SRE etc.

Any courses on frameworks such as ASP.NET, Ruby on Rails or Django would be great. I can see the complexity arising in creating in-browser tutorials involving any backend or framework etc. But I think it will add tremendous value to the platform.

subrat_rout··on We Need a Yelp for Doctoral Programs
To add on top of it, majority of graduate students are from countries like India and China and their life/career is tied to F1 visa status which make students even more vulnerable to disclose any sincere/legit info. about the program they are in.
subrat_rout··on Wealth Inequalities Shown to the Scale
You can press -> key of <- ->to scroll to right.
subrat_rout··on Ask HN: Can I get some opinions on best alternatives to Digital Ocean?
It depends what you will be using for. I have been using Hetzner and happy with them. Mind you the customer services is next to none. So if you are a guy who wants to invest some time and learn by doing then it is a great deal. I have seen nobody is close to it's price point not even AWS.
subrat_rout··on Bosch develops rapid test for Covid-19
In addition to all information above this test is able to detect antibodies only not virus. So it is not recommended tests by WHO. This test is only useful in the later part of infection by the time which patient might have in contact with others thus spreading the disease. We need tests which can detect single of very few virus particle in the early stage of infection and that will help to quarantine the patient thus reducing virus spread.
subrat_rout··on Ask HN: What was your biggest failure in 2019?
I wish you good luck. I was in your place couple of years ago. The only way out of this situation is to apply. As from the other post that you have had somebody has already mentioned, you probably did not have many opportunities due to holiday window. I suggest you double down and start applying and interviewing from Jan 2020. Trust me, this is just a number game. And as others have said, nobody is not 100% sure how to properly interview a candidate or find a great developer.
subrat_rout··on Ask HN: How to stand out as a junior engineer
Not to sound negative but if a junior developer can create a profitable startup and hire several employees then why he/she would go to knock doors for a job? If I can have a profitable project then I can hire a senior dev full-time or part-time to mentor/teach me. Right?
subrat_rout··on How much money do people need to be happy?
Joking aside, I guess as a person with such amazing credentials, making $20k+ per month for you should be a cakewalk. By American standard it should be a decent mount of money to raise family with kids. But if you want to travel the world, eradicate poverty, leaving trust fund for kids then yes the number can be stretched infinitely. As a married person with kids I would be very happy making the amount of money you have mentioned passively.
subrat_rout··on PSA: Check your inbox for email from stellar.org, you may be sitting on $
Is it like whoever signed up got 6000 coins? When I checked my email I found out also I have signed up for stellar and tried to recover the account using recovery password. Now I am not seeing any private/public key for the old account and the balance also shows me as zero. Not sure what happened.
subrat_rout··on Ask HN: How to get industry insights and meet people outside your bubble?
Thank you.
subrat_rout··on Ask HN: How to get industry insights and meet people outside your bubble?
I would love to read your blog post. Thanks in advance.
subrat_rout··on Ask HN: I have 1k to invest, what would you recommend?
Fair enough, thank you.
subrat_rout··on Ask HN: I have 1k to invest, what would you recommend?
In one of your previous post you mentioned using python. May I know your roadmap of learning the python and using it? Not asking you to divulge your trading strategy.
subrat_rout··on Ask HN: What coding challenge sites should I try next?
I am surprised no body has mentioned Exercism yet. Go to exercism.io and there are around 60 problems for PHP that you can start working on it. The good part is, it has tests built into it. You can gradually work on a solution by progressive approach and thus passing each test successively.
subrat_rout··on Ask HN: What are your views on India based development agencies?
Being originally from Odisha I am curious to know the name of the company.
subrat_rout··on IoT on Rails (looking for feedback)
Just sent you an email. Thanks
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