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itschekkers

127 karma · joined January 25, 2016

@itschekkers
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itschekkers··on Bessemer Ventures Anti-Portfolio
this is really just self-congratulation by them about how they have strong deal flow.

they also use this as a disingenuous/insincere way of rejecting founders (we don't want to invest, but you're probably one of the other unicorns we didn't invest in! check out out antiportfolio!)

itschekkers··on When good ideas make bad business
i'm interested in the project you mentioned-- drop me an email adam at springhealth.com if you'd like to chat
itschekkers··on Bad Times in Tech? Not If You’re a Startup Serving Other Startups
There's always a PG article -- http://www.paulgraham.com/submarine.html [April 2005]
itschekkers··on Cameo raises $50M to deliver personalized messages from celebrities, influencers
agreed
itschekkers··on Stripe Chargeback Protection
you should look into chargehound[chargehound.com], i think they would work for you.
itschekkers··on Full Shutdown of L Train to Be Halted by Cuomo
i think its because they are correcting for the commuter tax deduction. ask your HR folks about https://www1.nyc.gov/site/dca/about/commuter-benefits-law.pa...
itschekkers··on Association between physical exercise and mental health: a cross-sectional study
thanks! <3

we've had a wonderful positive response to this article, and people are overwhelmingly excited and motivated to try and exercise more because of it (even at relatively lower intensities or volumes -- every little helps). even if we are extremely cynical and say theres zero benefit of exercise for mental health, then people will still be getting known improvements regarding diabetes, stroke, cardiovascular disease. Nobody is advocating for exercise at the expense of alternative treatments like meds or therapy, this really is just a (potentially large) extra benefit.

itschekkers··on Association between physical exercise and mental health: a cross-sectional study
1- surely we're allowed to waste our own time if we like!

2- nope, and actually my entire research agenda has been around helping people find a treatment that is most likely to work for them specifically! (we also founded a company to bring the research to market- springhealth.com)

3- that is beyond the scope of the paper, and we didnt use the word hospitalized once

4- yep, and thats a good example of one of the pitfalls of self-reported surveys. in general, i am a bit less cynical and in our experience, most people aren't filling out surveys to intentionally lie or sabotage.

hope this helps!

itschekkers··on Association between physical exercise and mental health: a cross-sectional study
Original Article author here - happy to help with any questions people have.

Also sorry about the paywall - you can get the article either through sci-hub here http://sci-hub.tw/10.1016/S2215-0366(18)30227-X or you can email me and i'll send you a copy direct!

itschekkers··on Google Is Training Machines to Predict When a Patient Will Die
I hate to pour cold water on this, but medical researchers have been predicting mortality for years.

For example, here's a paper from the 1980's also predicting when a patient will die, also using a couple of thousands of patients' data: http://europepmc.org/abstract/med/3816253

And, Google's paper wasn't published in Nature, it was in a new open access journal owned by Nature. In academia, that is like the difference between a really fancy porsche, and a really cheap volkswagen (two very different things, both owned by the same company).

itschekkers··on Comparative efficacy and acceptability of 21 antidepressant drugs
placebo rates would be something in the 15-40% remission rate range, in small RCTs. it varies more than you would think from one trial to another. antidepressant efficacy would be something like 20-45%. recovery rates are usually higher in smaller trials, and lower in bigger trials, partly because people get more high-touch service in smaller academic studies
itschekkers··on The hippocampus as a 'predictive map'
theres a website called sci-hub (which maybe illegal) that you can use to get almost any paper in a STEM field, especially from major journals. you type www.sci-hub.cc/ and then paste the DOI of the paper. it takes you straight to the pdf!
itschekkers··on Toward a Predictive Theory of Depression
Chekroud (2015) here - just wanted to say that I think SSC is awesome, and does a terrific job discussing complex problems in psychiatry & philosophy.
itschekkers··on Stack Overflow Salary Calculator
even in Greenpoint/Williamsburg/Bed-Stuy/Hoboken you're still paying 1500 a month to share with a few roommates though.
itschekkers··on Mercury Protocol: Communication Platform Built on the Ethereum Blockchain
This post made me remember that I had muted "blockchain" on twitter, and my life was much better because of it. Classic example of adding "blockchain" or "token" to something for pure hype.
itschekkers··on I’m Peter Roberts, immigration attorney who does work for YC and startups. AMA
I am a client of PR, and I am algerian :)
itschekkers··on Show HN: RNN that generates Game of Thrones text
I wonder if there are any forums/fan fiction websites where you could find big chunks of prose to add to the training data. Might help bring the loss down a bit if you mix some in.
itschekkers··on Painting with Code: Introducing our new open source library React Sketch.app
+1 for this idea!
itschekkers··on Python vs. R: The battle for data scientist mind share
Ya, completely agree with this (having also used both extensively). dplyr can also connect to remote SQL server so data don't have to be local. Maybe pandas does this now too but in my experience SQL connections were generally more painful in python
itschekkers··on Deep learning with text: Learning when to skim and when to read
my impression was that this was about the time taken to make each prediction, not to train the model? and yep, looking forward to the paper!
itschekkers··on Deep learning with text: Learning when to skim and when to read
cool paper, i enjoyed following the post (and really appreciated the effort put into the bokeh viz!)

i wonder if this would have been improved by being clearer about the motivation. the authors frame it as though the ~60ms penalty for using the LSTM for prediction is a huge burden, and i can imagine situations where it is. however, it seems like if this is the case, we need some real life/"scaled out" examples of how this solution would work in practice. e.g. how long does the decision logic take to execute (maybe 5ms?); what proportion of the time will you have to run the LSTM after the BoW model anyway? note that those instances you are now worse off than just running the LSTM in the first place (total time = BoW time + decision time + LSTM time). once you have all these you can run the math and know (on average) how much time you'll actually save, and how much performance you sacrifice

itschekkers··on Married to someone with anxiety
hey, I'm not from YC nor am I rich, but we have recently founded a startup (www.spring.care) developing tools that help depressed patients identify the best antidepressant for them. I'd love to do something similar for Anxiety, or help you do it yourself. feel free to reach out to us through the website
itschekkers··on How Quid uses deep learning with small data
really nice article -- easy to follow, sensible steps, clean code. I haven't done too much text ML and this was a nice piece to follow - thanks!
itschekkers··on Supervised Learning and Unsupervised Learning
It is pretty obvious that the title is unnecessarily gendered, and that in this case it plays into broader stereotypes about women in STEM fields. I'm not sure why you are so insistent on defending it -- this is exactly the kind of thing that needs to stop happening if we really want a more inclusive atmosphere in the field.
itschekkers··on One Road Out of Depression
Thanks for sharing your experiences. I'm glad you made it through. I'm a researcher at Yale, and we've been developing algorithms to figure out which antidepressant is most likely to help a specific patient. We want to help patients get back on track sooner, to help minimize suffering. We've published our research, and made our algorithm available online through our startup (www.spring.care/spring-assessment). If you know of any other friends or family that are struggling with depression, please do let them know about our work, and I hope that they find it helpful
itschekkers··on One Road Out of Depression
Sorry to hear about your experience, but I'm glad you have found ways of managing symptoms. Like you say, people absolutely do respond differently to different medications. I'm a researcher at Yale, and we've been developing algorithms to figure out which antidepressant is most likely to help a specific patient. We've published some papers, and made our algorithm available online through our startup (www.spring.care/spring-assessment). If you find it helpful, please do send us feedback!! hello at spring dot care
itschekkers··on LightGBM – A fast, distributed, gradient boosting framework
looks nice, especially in reducing memory use. it would have been great if they built in k-fold cross-validation by default too
itschekkers··on Open Guide to Amazon Web Services
applied ML research here also -- a lot of interactive (but highly parallelizable) modeling, graphing. Using medium-size data sets around 3-4GB in ram, by the time you forked it a few times, you easily end up beyond the m4.10xlarge or c4.8xlarge limits.

IMO theres an awkward space between small data and big data where it isn't really worth spending a long time to treat it like a real "big data" problem, and the x1 instance gives you an easy-out.

itschekkers··on Predicting the Popularity of GitHub Repositories
Umm they use the first 6 months of data in the model. How is it surprising that trajectory of stars in first 6 months predicts the rest of the trajectory.....
itschekkers··on Felony – An open-source PGP keychain
I like the idea of this, and would love to give it a try. I would say, however, that the documentation/instructions are a little bit barebones. I know its just early days, but as a newcomer to node it is pretty difficult to know how to use this. You may also want to include a PGP 101 (or a link to a good get-started guide) because it isn't really common knowledge either