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phonypc

918 karma · joined February 17, 2019

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phonypc··on Covid-19 Mortality Risk Correlates Inversely with Vitamin D3 Status
>after that abstract I'm not sure I want to check out the details

There's a fairly short review of why the study is kinda silly here: https://gidmk.medium.com/vitamin-d-covid-19-and-the-promise-...

phonypc··on Covid-19 Mortality Risk Correlates Inversely with Vitamin D3 Status
Nah it's just a comically absurd proposition, even if you take the implication that low D3 is causing COVID mortality at face value.

Obligatory relevant xkcd https://xkcd.com/605/

phonypc··on Swedish nationwide study: vaccine effectiveness lower and waned faster in men
I'm not sure I'd call that hypertension difference small, and it's by far not the largest difference. There's ~30% more diabetes in the vaccinated cohort. 2x the rate of kidney failure.
phonypc··on Swedish nationwide study: vaccine effectiveness lower and waned faster in men
Looking at the first table, the vaccinated cohort was obviously WAY less healthy to begin with. As expected; sick people were more inclined to protect themselves. Especially with the cutoff for inclusion being May 2021, presumably before younger, healthier people were being vaccinated.

Am I missing something in the methods that would control for this or... is it just that dumb?

phonypc··on In Re-Analysis, Ivermectin Benefits Disappeared as Trial Quality Increased
Not a stats expert, but this just seems like a (intentional?) fundamental misconstruing of meta-analysis. My understanding is they correct for random error, not error due to flawed study design.
phonypc··on I made my own garum
I wouldn't be surprised if the price went up if it became popular at its price. Definite Veblen good vibes.
phonypc··on I made my own garum
You can get very premium Vietnamese fish sauces (also just anchovies and salt) which are smoked and aged in Bourbon barrels for years... for about 1/3rd the price.
phonypc··on I made my own garum
That is exorbitant for anchovies + salt + time. It could be half the price and still marketed as a premium, niche thing.
phonypc··on I made my own garum
The article the author links at the end of the thread goes into this a bit.

>Sally Grainger, an independent researcher and author of The Story of Garum, published last December, also praises Palacios’ effort. But she believes that what the Cádiz team actually produced was a form of liquamen, and because they combined techniques from different recipes, she doubts whether their claims of authenticity are completely justified.

phonypc··on Culinary detectives try to recover the formula for garum
There's no indication that low-salt garum was a thing. That would just be horribly spoiled fish juice.

People probably weren't in the habit of consuming things that reliably made them sick or dead.

phonypc··on Culinary detectives try to recover the formula for garum
>disappeared completely

Not really. It evolved into things like Worcestershire, ketchup and a bunch of less known sauces. Colatura di alici is probably closest in spirit to the Roman preparation.

phonypc··on Scientists recreated classic origin-of-life experiment and made a new discovery
It doesn't tell us nothing, it's just not the whole story. And why should one expect a single experiment to tell the whole story?
phonypc··on Cheap antidepressant shows promise treating early Covid-19
I'm not sure you can apply those findings regarding antioxidants. NAC isn't itself an antioxidant, but a prodrug for an amino acid that is the rate limiting factor in producing glutathione, the bodies primary endogenous antioxidant. Presumably if you're already "full" on glutathione, the NAC does nothing.
phonypc··on “Dune” (The Movie), Annotated
The emperor and Irulan only make a personal appearance at the end of the book, don't they? During events the movie presumably doesn't cover at all?
phonypc··on Show HN: CookLang – Recipe Markup Language
Looks to be floury/soft.
phonypc··on Show HN: CookLang – Recipe Markup Language
Hard/soft presumably corresponds to the waxy/floury categorization Anglo countries often use. It shouldn't be hard to find which category a given variety of potato better fits into.
phonypc··on Show HN: CookLang – Recipe Markup Language
I very much doubt that most recipe timings actually involve a timed test cook at all. They're just guesstimates.
phonypc··on I’ve been reading a whole lot about tomatoes
Little hyperbolic there. Pure fat is only about 50x as calorie dense as the subject tomatoes. It would take some very fatty meat to get to 20x.
phonypc··on I’ve been reading a whole lot about tomatoes
Did you miss the part before your quote about them being a moderate source of vitamin C? The whole sentence needs a re-write anyway IMO, "no significant nutrient content" seems like too strong a statement given the table. A large tomato would cover ~10%DV of a whole bunch of vitamins and minerals.
phonypc··on Two conspiracy theories about cola
How do you imagine the carbon makes it from the sugar and into the components of new/larger cells? Magic? It has to be metabolized first. In the gut, mostly through fermentation.
phonypc··on Two conspiracy theories about cola
Worth noting that the "in mice" qualifier might be particularly apropos here.

>According to Taylor, the observations in mice make sense from an evolutionary perspective. "In mammals, especially hibernating mammals in temperate climates, you have fructose being very available in the fall months when the fruit is ripe," he said. "Eating a lot of fructose may help these animals to absorb and convert more nutrients to fat, which they need to get through the winter."

Humans generally don't hibernate.

phonypc··on Two conspiracy theories about cola
Uhh... sure. If you don't want to call it fermentation that's ok. Though I don't imagine human gut bacteria are respirating, or some other more exotic form of metabolism.

Point is, the products of bacterial metabolism of sugar in the human gut tend to cause issues, as in lactose intolerance, or the more rare sucrose intolerance. Hence my request for a citation on fibre delaying absorption of fructose so that "bacteria get most of it".

phonypc··on Two conspiracy theories about cola
>fructose absorption is delayed long enough that gut bacteria get most of it

Have a reference for this? Seems implausible, bacterial fermentation of any sugar in the intestines should result in distress, i.e. the same symptoms a lactose intolerant person would have upon drinking milk.

phonypc··on Ivermectin shows that not all science is worth following
A collection of links to studies would be harmless. The site purports to compile data from said studies in a meaningful and complete manner. It very much does not.

There are also issues with some of the studies themselves, but that's a separate issue.

phonypc··on Ivermectin shows that not all science is worth following
No, I'm (me, singular) close to assuming that people who link to an anonymous, mangled cherry-picking of incongruous study endpoints is a paid shill.
phonypc··on Ivermectin shows that not all science is worth following
That website is such obvious bunk that I'm close to assuming anyone still linking it is literally a paid shill. They still have a copycat up in hcqmeta.com touting similar claims for hydroxychloroquine. And a dozen other drugs/vitamins.

Here's a nice read on the subject: https://threadreaderapp.com/thread/1422044335076306947.html

phonypc··on EU scientists reveal long-term brain damage caused by Covid
The age and sex disparity in post-vac myocarditis would seem to disqualify that hypothesis. It's not like young men have veins in their deltoids where other demographics don't.

Tasting saline after an IV injection in nonsensical.

phonypc··on Ivermectin shows that not all science is worth following
The lousy studies aren't lousy because of the constraints of an insufficient budget. They're based on fraudulent/fabricated data.

As far as the "real world trial" of India, the peak of their delta wave roughly coinciding with an updated treatment guideline including ivermectin is hardly strong evidence.

A) Correlation isn't causation.

B) An updated treatment guideline doesn't indicate people were actually taking ivermectin.

C) Using it as a treatment (i.e. after a case occurs) can't possibly be responsible for preventing cases. There was some buzz about it being offered as a prophylactic, but it never panned out.

D) The peak of the wave coinciding with the update necessitates that the reproduction rate was dropping before the update

Further, just look at Peru for a clear demonstration that it isn't the miracle some would like to believe it is.

phonypc··on No time to die: An indepth analysis of James Bonds exposure to infectious agents
The "study" has nothing to do with the latest movie, other than using its title as a pun.
phonypc··on Chilling Effects
CO2 will be elevated in a stuffy room, but that's not actually what you're noticing. It's humidity and VOCs.

If CO2 was actually high enough to be a problem, the first symptoms would be an increase in heart rate and rate of respiration. Kinda the opposite of lethargy.

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